A stand up pouch can protect extremely well when you choose the right barrier and closure. Focus on: protection against air and moisture, the right structure keeps your product fresh. Protection against light, choose an opaque or metallized layer if light is harmful. Resistance to impacts, drops and stacking, use the right film thickness, strong seals and a stable bottom. Good reclosure, use a zipper, valve or spout for leak tight opening and closing. Heating during production, if you pasteurize or sterilize, choose a retort pouch. Practical checks: request samples, test seal strength, do drop and stacking tests and run a short shipping trial.